Vagifem 10 Estradiol Vaginal Inserts
Estradiol vaginal inserts

Get your Vagifem medication filled online

With Felix, you can get Vagifem 10 prescribed by a licensed healthcare practitioner and delivered to your door for free.

At a glance
10 mcg vaginal tablets
Why Felix
Prescribed by a Canadian healthcare professional
Support and resources along your journey
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What is

Vagifem 10 is a medication that contains the hormone estrogen (estradiol).

It’s used as a treatment for the symptoms of vaginal atrophy, which is caused by low levels of estrogen in the body.

The Vagifem dosage recommended for you, will depend on what your healthcare practitioner believes is best for you, based on your current health and medical history.

For more resources, including a full list of the risks and benefits of Vagifem 10, please review the product monograph.

How does

Vagifem 10 contains estrogen (estradiol), which is a natural hormone produced by women.

However, throughout the menopausal transition, the ovaries will slow and then stop production of estrogen.

In these cases, Vagifem 10 can be used to replace this missing estrogen and help reduce dryness or vaginal pain during the menopause transition.

What is
used to treat?

Vagifem 10 is indicated for use as a treatment to help treat the symptoms of vaginal atrophy due to low estrogen. It’s also used to reduce certain menopause symptoms, in people that are either perimenopausal or menopausal.

It does this by replacing estrogen that is missing from the body, due to the natural changes that occur during the menopausal transition and life stage.

How do you take

Each 10mcg dose of Vagifem 10 comes preloaded into the applicator for use.

Vagifem vaginal estrogen tablets are designed to be used as vaginal inserts, which means that they need to be inserted into the vagina to work.

If you have any questions about how to use the applicator, you should talk to your healthcare practitioner at Felix.

They’ll be able to give you any additional direction you need to comfortably and effectively use your Vagifem vaginal pills.

How long does
last after you take it?

What are the common side effects of

Many people that use Vagifem 10 won’t experience any side effects from use.

However, it is possible that you could experience:

  • Breast edema
  • Breast enlargement
  • Breast pain or pain tenderness
  • Peripheral edema (swelling of arms or legs)
  • Genital infection with a fungus or vaginal inflammation
  • Headache
  • Dizziness
  • Nausea
  • Diarrhea
  • Feeling tired
  • Abdominal pain (stomach)
  • Distension or discomfort
  • Vaginal bleeding, discharge or discomfort
  • Back pain
  • Weight gain
  • Acne, rash, or itchy skin
  • Muscle spasms
  • Pain in extremities
  • Anxiety
  • Trouble sleeping
  • Heart palpitation
  • Urinary tract infection
  • Allergic reaction

If any of these side effects become severe, you should talk to your healthcare practitioner right away. They may want to suggest an alternative menopause treatment that could work better for you.

Menopause Hormone Therapy (MHT) with Vagifem 10 and estrogen-therapy can increase the risk of other conditions that you should know about. MHT is the most effective treatment for menopausal symptoms and has been shown to prevent bone loss.

In menopausal women who start appropriately-dosed MHT prior to age 60 OR within 10 years of their last period, the health benefits outweigh the risks.

Risks of MHT are considered very rare (~1 case per 1000 to 10,000 women on MHT per year) and may include:

  • risks of stroke or blood clots in legs or lungs with oral estrogen (much lower risk with estrogen gel or patch)
  • risks of dementia in women older than 65 years,
  • risk of breast cancer (less than ~1 case per 1000 women on MHT per year)  

These conditions are all rare, but they highlight the importance of having a full discussion with your healthcare practitioner; especially if you’re experiencing moderate to severe side effects.

Individualization is key, and your MHT treatment plan should be reassessed (at least) once a year to monitor your health, as well as ensure that you are on the correct dosage and formulation. Your practitioner can help you find balance between treating your symptoms safely, and avoiding increased risks

Who shouldn't take

You shouldn’t use Vagifem 10 if:

  • You have a thicker than normal uterus lining  (endometrial hyperplasia)
  • You have or may have estrogen-dependent cancers
  • You have, have had, or have reason to believe you might have breast cancer
  • You’re experiencing unusual or unexplained vaginal bleeding
  • You’re pregnant, think you may be pregnant, or are breastfeeding
  • You have blood clotting problems (deep vein thrombosis, pulmonary embolism, thrombophlebitis)
  • You have a blood pigment disease (porphyria)
  • You have or have had liver issues, including blood tests showing your liver is not working properly
  • You’ve had a heart attack, stroke, blockage, or narrowing of the arteries of the heart (coronary heart disease)
  • You have eye problems caused by low blood flow to the eye
  • You’re allergic to estradiol or any of the other ingredients in Vagifem 10 or the container

In addition to these concerns, you should be sure to talk to your healthcare practitioner before starting Vagifem 10 if you:

  • Have a history of drug allergies or intolerances
  • Have a history of breast disease, breast lumps and/or breast biopsies
  • Have a family history of breast cancer
  • Have or have had uterus problems, including uterine fibroids, endometriosis, a history of endometrial hyperplasia, or a hysterectomy
  • Have a history of liver problems, jaundice, or itching
  • Have a history of migraines
  • Have high calcium in your blood, as a result of kidney disease or cancer
  • Have or have had high blood pressure
  • Have symptoms of a blood blockage to the brain (i.e., headaches, trouble speaking, paralysis, loss of consciousness)
  • Have systemic lupus erythematosus (an autoimmune disease)
  • Have a history of high cholesterol or high levels of other fats in the blood
  • Have or have had kidney disease
  • Have or have had asthma
  • Have or have had epilepsy
  • Have diabetes
  • Have otosclerosis (an ear problem)
  • Think you have a vaginal infection
  • Smoke

These other factors could increase your risks of experiencing negative or severe side effects. However, your healthcare practitioner may be able to suggest alternative menopause medications, which will work better for you based on your health and medical history.

Tell your healthcare professional about all the medicines you take, including any drugs, vitamins, minerals, natural supplements or alternative medicines. The following may interact with Vagifem® 10: 

  • Medicines that impact liver enzymes
  • Phenobarbital, phenytoin, carbamazepine, used to treat epilepsy and seizures
  • Ritonavir and nelfinavir, used to treat HIV/AIDS
  • Anti-infective medicines such as rifampicin, rifabutin, nevirapine, efavirenz
  • St. John’s Wort, used to treat depression

What happens if
is taken regularly by men?


We’d love to tell you more

Health Canada regulations require us to confirm your patient status to access further information on Vagifem-10.
The drug identification number (DIN) is easy to find. It’ll be printed on your Vagifem-10 packaging and the receipt from your pharmacist.

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Trusted by over 500,000 Canadians

Very easy and professional experience. Quick response from the doctor and easy ordering, billing and shipped and delivered on time. Hassle free.
Great service and products. Everything always arrived in a timely manner.
Simple, respectful, professional with good follow up and guidance, and fast service and delivery.
Best place to get birth control. No more annoying doctor visits
Within an hour . . . a doctor contacted me to make sure that particular medication was what I wanted. Doctor was friendly and knowledgeable. Within minutes . . . being confirmed my order was put through and I received my medication after 2 days.
Great service! I really appreciate being able to put my auto-refill on pause.
Easy and simple.
The best service!!! So happy I never have to try and get myself to the pharmacy anymore. This is the future!!!
The whole process of signing up with Felix, the online visit, and getting my prescription in the mail was very easy and very convenient.
Super convenient, and amazing customer service! The team always responds +++ fast and answers every question and concern. Very pleased with Felix!
Discreet, quick, very professional, and feels totally safe. This is such a convenient service and I'm a huge fan already.
Sign up was a breeze, and items shipped faster than expected. A positive, painless experience from start to finish!
Felix gets you into contact with doctors discreetly online to address personal matters that you'd rather not go to a doctor in person to see, you get the prescription best suited to your needs, and they'll deliver it to your local pharmacy or even your house!
Very quick and easy to do. Can ask the doctor any questions about the medication.
The process was a whole lot easier and faster than I imagined. And the doctor was absolutely helpful and answered relatively fast. I highly recommend Felix.
Super convenient and affordable! Much easier than having to book a doctors appointment and wait to get a prescription filled.

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Frequently asked questions


How do I get a Vagifem 10 prescription?

In Canada, to get a Vagifem prescription, you must first speak with a licensed healthcare practitioner, like the experts at Felix.

Felix is making this process quick and convenient for Canadians by providing online assessments with licensed healthcare practitioners.

If they believe that Vagifem 10 is right for you, based on your health and medical history, they can offer you a prescription.

Can I get a Vagifem 10 prescription online?

Yes, you can. However, to get a Vagifem 10 prescription online in Canada, you must first speak with a licensed healthcare practitioner, like the ones you’ll find at Felix.

If the practitioner believes that Vagifem 10 could be right for you, based on your current health and medical history, they’ll be able to provide you with a Vagifem 10 prescription.

Do I need an appointment to get a Vagifem 10 prescription in Canada?

No, Felix is eliminating the need for long wait times at doctor’s offices, or to wait weeks for a routine appointment.

Just complete an online assessment, and if your healthcare practitioner believes that Vagifem 10 is right for you, they’ll be able to write you a prescription.

Best of all, Felix can deliver your medication directly to your doorstep, at no extra cost.

Can I buy Vagifem 10 online?

In order to buy Vagifem 10 online in Canada, you must first have a prescription from a licensed healthcare practitioner, like those at Felix. Complete an online assessment, and if your healthcare practitioner believes Vagifem 10 is right for you, they can write you a prescription for it. Best of all, Felix can deliver your medications discreetly to your home, at no additional cost to you.

Is Vagifem 10 available over-the-counter?

No, Vagifem 10 is not available over-the-counter in Canada. This means that you’ll need to speak with a licensed healthcare practitioner in order to access this medication.

Thankfully, Felix is making this process comfortable and seamless for Canadians. Just complete an online assessment with one of Felix’s healthcare practitioners.

If they believe Vagifem 10 is right for you, they can provide you with a prescription, and then have your medication shipped to your home for free.

Is Vagifem 10 covered by insurance?

This is a question that’s best asked to your insurance provider, since each person’s coverage will look a little different.

The good news is that if your insurance company does cover Vagifem 10, Felix can bill your insurer directly, and then deliver your medication right to your door. No pharmacy pick-up required.

It's important to note that insurance coverage for online medications through Felix doesn't include the cost of your assessment.

Felix 101

What is Felix?

Felix is Canada’s first truly integrated healthcare platform. We provide on-demand treatment for everyday health needs like weight loss, mental health, sexual health, and more. Founded in 2019, our digital-first approach to healthcare includes everything from diagnosis to prescription — all accessible from the comfort of home.

Who can use Felix?

Anyone who is 18 years or older older (16 or older for acne and birth control prescriptions), and is located in Alberta, British Columbia, Manitoba, Newfoundland and Labrador, Nova Scotia, Prince Edward Island, Saskatchewan or Ontario. We cannot ship medication outside of these provinces at this time.

Does Felix replace my doctor?

No. Felix provides a faster, hassle-free way for you to get a prescription to certain medications but our service does not replace your primary care provider. For matters that extend beyond obtaining a prescription lifestyle medication safely and easily, we encourage you to consult your primary health practitioner in person — whether for checkups, personal health concerns, or to inform them about the medications you are currently using.

Can I be accurately assessed remotely?

Absolutely. Our online assessments have been designed to ask all the necessary questions required for diagnosis. We've worked with specialist to create an assessment process that can provide sufficient information for the healthcare practitioner to determine whether or not you are eligible for a prescription and craft an appropriate treatment plan.

It's an emergency. What do I do?

Call 911 or proceed to your nearest emergency room immediately. Felix is not intended for medical emergencies. Once the emergency has been addressed or resolved, contact your prescribing practitioner to inform them of your experience as this may impact your current treatment plan.

Online Visits

How does this visit work?

After creating an account, you will complete a medical assessment for evaluation by one of the Felix healthcare practitioners. 

During your assessment, you will have the opportunity to send your practitioner questions via secure messaging.  

In most cases, practitioners will complete your assessment with secure messaging alone but sometimes they may determine you require an audio or video visit and/or further diagnostic testing to help determine the best treatment plan for you. 

If your practitioner has determined a prescription treatment is appropriate, they will approve your visit and write you a prescription. Our pharmacy will then ship your prescription to your home.

You’ll be able to message your healthcare practitioner if you have questions about your medication or want to make changes to your treatment at any time.

Do I need to complete my online visit at a scheduled time?

No. We use an asynchronous telemedicine model so you can complete your online visit in your own time and we save your progress so you can come back later to finish it.

If you are completing a visit in the mental health or weight loss categories, your healthcare practitioner may require a phone or video call to discuss your medical profile further during the assessment process.

Does the online visit require a phone or video appointment?

Most assessments do not require a phone or video conversation. Once a prescriber has reviewed the info in your assessment they will respond to you via secure instant messages that you can access within your Felix account.  

If you are completing a visit in the mental health or weight loss categories, your healthcare practitioner may require a phone or video call to discuss your medical profile further during the assessment process.

How quickly will a healthcare practitioner review my online visit?

You can expect to receive a response from a healthcare practitioner within 24 hours of submission. If you’ve been waiting longer than this, please email and we’ll look into it.

Can I just get the medication and skip the online visit?

No. A prescription written by a licensed healthcare practitioner is required for all medication currently provided through Felix’s service. If you already have a prescription with at least one refill remaining, you can transfer it to the Felix Pharmacy network.

Please email our Customer Support team at and they will be able to assist you with the transfer.


How long will it take to get my medication?

Not long. After completing your assessment, a practitioner will generally respond within 24 hours, and often much sooner.

The pharmacy will process and fill your prescription within 2-3 business days of your prescription approval date if there is nothing blocking them from doing so.

All packages are shipped via Express Post, which usually takes 2-3 business days. You will receive an email with your tracking number once your treatment has been shipped.

Is your packaging discreet?

Absolutely. All Felix shipments arrive in a nondescript blister package so you can have your medication shipped wherever makes sense for you as long as there is someone there to sign for it.

Do I have to be home to receive my package?

A signature upon delivery may be required.

How much does it cost for shipping my medication?

There is currently no cost to have your medication sent to you from our Felix Pharmacy network.

What courier do you use for shipping?

Our pharmacy partners use Canada Post and/or Purolator for shipping.

Privacy and Security

Is my information private and secure?

Yes, your security is paramount to Felix’s mission. Personal health information provided during your medical assessment is strictly and legally confidential between you and the Felix healthcare practitioner.

Beyond that, all your account information (including the medical assessment, credit card, and shipping information, etc.) is also stored safely and securely. Felix is compliant with all federal and provincial health privacy legislation. It is our duty to protect your data with comprehensive security infrastructure and stringent data policies to ensure it stays private and secure.

Read more on our Privacy Policy.

Is this legal?

Yes! In Canada, only a licensed healthcare practitioner can write a prescription, and only a registered pharmacist can fill that prescription. We are supported by leaders in the Canadian pharmacology and specialized medical fields. Felix adheres strictly to all the regulations set forth by all applicable Colleges of Pharmacists and Colleges of Physicians and Surgeons in which we operate.

Is this safe?

Absolutely. All prescriptions obtained via Felix are provided by licensed Canadian healthcare practitioners—the same as you would get at a hospital, doctor’s office, or clinic. These practitioners do not provide prescriptions unless they deem it medically safe and appropriate to write them based on your medical profile and assessment answers. Our assessments have been crafted by the experts on our medical team. Finally, all Felix Pharmacies are provincially accredited just like any retail pharmacy.

How is my privacy protected?

Your privacy is our top priority. All your data is 256 bit SSL/TLS encrypted, and we take significant steps to keep your data secure. You can read our Privacy Policy for more information. 

Pricing and Payment

How much is the online visit?

Felix charges a fee for the online visit, but only if and when you are approved by the healthcare practitioner. In most cases the fee is $40 but varies by treatment category. The visit fee includes a prescription valid for up to a year (depending on the condition) and on-going support from the healthcare practitioner or pharmacist.

How much will my medication cost?

It depends. Medication costs vary from treatment to treatment but will be in line with what you would pay at a pharmacy in person. You will see the estimated cost of your medication before insurance, during the online visit but will only be charged once approved. Once approved, your prescription will be sent to the pharmacy and we will process the payment and fill the prescription within one to two days.

Keep in mind that you won’t necessarily need to pay the full price yourself. If you have insurance, Felix’s partner pharmacies will bill your insurer directly. You may also be eligible for financial support in your province.

What payment methods do you accept?

We accept all major credit cards for any aspect of your treatment not covered by insurance or other financial support

When am I charged?

You will be charged for the online visit as soon as it is approved by the healthcare practitioner. From there, and after your prescription is activated by the pharmacy, you will be charged the medication cost for each shipment based on your chosen refill schedule. If you have provided insurance or benefits coverage details, it will be applied according to your plan.


Am I covered by my insurance?

Medication coverage varies greatly between different insurance plans.

The good news is that if you are covered, Felix can bill your insurer directly, and then ship your medications right to your door at no additional cost to you. We recommend that you upload your private and/or provincial benefit card during the online visit so that our pharmacy partner can apply any coverage you are eligible for before shipping your meds.

Insurance coverage for medications through Felix doesn't include the cost of your visit.

Is the online visit covered by my insurance or provincial health plans?

A Felix online visit is considered asynchronous since it is conveniently completed through a secure chat bases system. Currently, asynchronous visits are not covered by insurance or provincial health plans so you will be charged a visit fee, depending on the category of treatment you are requesting.

Is the medication covered by my insurance or provincial health plans?

Medication coverage varies greatly between different plans, provinces, and has specific criteria that determine eligibility. For private insurance, we recommend contacting your benefits administrator with your details and the Drug Identification Number (DIN) and the drug name to determine your coverage.

For more details on provincial health plan coverage see below:

Alberta: Learn more about AHCIP here. Search for covered drugs here.

British Columbia: Learn more about MSP here. Search for covered drugs here.

Manitoba: Learn more about MHSIP here. Search for covered drugs here.

Newfoundland and Labrador: Learn more about MCP here. Search for covered drugs here.

Nova Scotia: Learn more about MSI here. Search for covered drugs here.

Ontario: Learn more about OHIP+ here. Search for covered drugs here.

Prince Edward Island: Learn more about Health PEI here. Search for covered drugs here.

Saskatchewan: Learn more about Saskatchewan Health Coverage here. Search for covered drugs here.

Is birth control covered by OHIP in Ontario?

OHIP+ covers some birth control for eligible residents of Ontario who are under 25 years old and do not have private insurance. You can check if your birth control medication is covered here. Make sure to upload your Ontario health card during your online visit so our pharmacy partners can apply your coverage directly.

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