Conjugated Estrogens Cream
Premarin Vaginal Cream
Premarin Vaginal Cream
Estrogen vaginal cream

Get your Premarin cream medication filled online

With Felix, you can get Premarin cream prescribed by a licensed healthcare practitioner and delivered to your door for free.

At a glance
Conjugated Estrogens Cream
0.625mg; 0.5g tubes
Why Felix
Prescribed by a Canadian healthcare professional
Support and resources along your journey
Free and fast shipping to your door
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What is
Premarin Vaginal Cream

Premarin cream is a topical vaginal hormone treatment containing conjugated estrogens.

This conjugated estrogen vaginal cream is used to treat vaginal and vulvar atrophies, as well as kraurosis vulvae (itching, burning, dryness in or around the vagina, difficulting or burning while urinating) that’s associated with menopause.

Premarin cream is also used to treat dyspareunia (pain during intercourse) associated with menopause.

For more resources, including a full list of the risks and benefits of Premarin cream, please review the product monograph.

How does
Premarin Vaginal Cream

Estrogens are a naturally producing female hormone that either lowers, or stops being produced entirely, during the menopause and postmenopause life stages.

Premarin cream contains estrogen that can replace this hormone as the body begins producing less naturally.

In turn, this helps reduce some of the side effects that are associated with menopause.

What is
Premarin Vaginal Cream
used to treat?

Premarin cream has two primary uses:

The first is as a treatment for vaginal and vulvar atrophies, as well as kraurosis vulvae. This treats symptoms such as:

  • Itching
  • Burning
  • Dryness in or around the vagina
  • Difficulty urinating
  • A sensation of burning while urinating

The second use is as a treatment for dyspareunia, which means pain during intercourse.

How do you take
Premarin Vaginal Cream

There are six steps to follow in order to take your dose of Premarin cream:

  1. Remove cap
  2. Screw nozzle end of applicator onto the tube
  3. Gently squeeze the tube to force sufficient cream into the barrel to provide your prescribed dose
  4. Unscrew applicator from the tube
  5. Place the applicator into the vaginal opening
  6. To release medication, press plunger downward

The Premarin cream dosage is managed by using the barrel to measure the proper amount. Always follow the dosing instructions exactly as instructed by your healthcare practitioner.

Never take a higher dose or use Premarin cream more often than prescribed, or it could lead to negative side effects.

How long does
Premarin Vaginal Cream
last after you take it?

What are the common side effects of
Premarin Vaginal Cream

Some of the side effects that could occur from using Premarin cream include:

  • Breast pain
  • Lactation (leaking of milk from the nipple)
  • Vaginal inflammation, itching, and/or discharge
  • Breakthrough bleeding, spotting, changes in menstrual flow, or painful periods
  • Joint or leg pain
  • Hair loss
  • Changes in weight (either increasing or decreasing)
  • Nausea
  • Vomiting
  • Bloating
  • Abdominal pain
  • Dizziness
  • Headaches or migraines
  • Changes in libido
  • Mood changes or irritability
  • Itching, rashes, hives, or tender red nodules on the shins or legs
  • Acne

If any of these side effects become severe, be sure to talk to your healthcare practitioner at Felix. They may be able to suggest an alternative dosage or medication that may work better for you.

Who shouldn't take
Premarin Vaginal Cream

There are certain people that should avoid using Premarin cream, such as:

  • People with known, suspected, or a history of breast cancer
  • People with known or suspected hormone-dependent cancer
  • People with unexpected or unusual vaginal bleeding
  • People who have or have had blood clotting disorders
  • People with serious liver disease
  • People with active or a history of heart disease, heart attacks, or strokes
  • People that are pregnant, or suspect that they may be pregnant
  • People who have vision issues due to blood vessel disease of the eye
  • People with an overgrowth of the lining of the uterus
  • People who have known abnormality of the blood clotting system that increases their risks of clots (i.e., protein C, protein S, or antithrombin deficiency)
  • People who experience migraines with or without aura
  • People who are allergic to any of the ingredients in Premarin cream

In addition to these people, there are others who should be extra cautious when taking Premarin cream. Be sure to talk to your healthcare practitioner if you:

  • Have a history of allergies or intolerances to any medications or substances
  • Have a history of breast disease, breast biopsies, and/or a family history of breast cancer
  • Have experienced any unusual or undiagnosed vaginal bleeding 
  • Have a history of uterine fibroids or endometriosis
  • Have a history of liver disease or jaundice, or itching related to estrogen use during pregnancy
  • Have a history of migraines
  • Have a history of high blood pressure
  • Have a history of kidney disease, asthma, or epilepsy
  • Have a history of bone disease
  • Have been diagnosed with diabetes
  • Have been diagnosed with a blood pigment disease (porphyria)
  • Have a history of high cholesterol or triglycerides
  • Have had a hysterectomy
  • Are pregnant or may be pregnant 
  • Have been diagnosed with hearing loss, due to bone problems in your ear (otosclerosis)
  • Smoke
  • Have been told you have a condition called hereditary angioedema, or have ever had episodes of rapid swelling of the hands, feet, face, lips, eyes, tongue, throat, or digestive tract
  • Have been diagnosed with lupus

Your practitioner may be able to suggest an alternative dosage or medication that will work best for you, based on your current health needs and medical history.

It’s important to note that Premarin Vaginal Cream may weaken and contribute to the failure of condoms, diaphragms, or cervical caps made of latex or rubber.

Tell your doctor or pharmacist if you are taking any other medications, including: 

  • Prescription medications
  • Over-the-counter medications
  • Vitamins or herbal products (such as St. John’s wort)

Some medications (such as medications for high blood pressure, diabetes, blood clots, sleeping, anxiety, seizures, pain-relief and tuberculosis) may affect how Premarin Vaginal Cream works.  Premarin Vaginal Cream may also affect how other medicines work.

What happens if
Premarin Vaginal Cream
is taken regularly by men?


We’d love to tell you more

Health Canada regulations require us to confirm your patient status to access further information on Premarin Vaginal Cream.
The drug identification number (DIN) is easy to find. It’ll be printed on your Premarin Vaginal Cream packaging and the receipt from your pharmacist.

Sorry the DIN you entered is incorrect. Please verify the number and try again.

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Trusted by over 1 million Canadians

Very easy and professional experience. Quick response from the doctor and easy ordering, billing and shipped and delivered on time. Hassle free.
Great service and products. Everything always arrived in a timely manner.
Simple, respectful, professional with good follow up and guidance, and fast service and delivery.
Best place to get birth control. No more annoying doctor visits
Within an hour . . . a doctor contacted me to make sure that particular medication was what I wanted. Doctor was friendly and knowledgeable. Within minutes . . . being confirmed my order was put through and I received my medication after 2 days.
Great service! I really appreciate being able to put my auto-refill on pause.
Easy and simple.
The best service!!! So happy I never have to try and get myself to the pharmacy anymore. This is the future!!!
The whole process of signing up with Felix, the online visit, and getting my prescription in the mail was very easy and very convenient.
Super convenient, and amazing customer service! The team always responds +++ fast and answers every question and concern. Very pleased with Felix!
Discreet, quick, very professional, and feels totally safe. This is such a convenient service and I'm a huge fan already.
Sign up was a breeze, and items shipped faster than expected. A positive, painless experience from start to finish!
Felix gets you into contact with doctors discreetly online to address personal matters that you'd rather not go to a doctor in person to see, you get the prescription best suited to your needs, and they'll deliver it to your local pharmacy or even your house!
Very quick and easy to do. Can ask the doctor any questions about the medication.
The process was a whole lot easier and faster than I imagined. And the doctor was absolutely helpful and answered relatively fast. I highly recommend Felix.
Super convenient and affordable! Much easier than having to book a doctors appointment and wait to get a prescription filled.

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Frequently asked questions

Premarin Cream

Felix 101

What is Felix?

Felix is Canada’s first truly integrated healthcare platform. We provide on-demand treatment for everyday health needs like weight loss, mental health, sexual health, and more. Founded in 2019, our digital-first approach to healthcare includes everything from diagnosis to prescription — all accessible from the comfort of home.

Who can use Felix?

Anyone who is 18 years or older older (16 or older for acne and birth control prescriptions), and is located in Alberta, British Columbia, Manitoba, Newfoundland and Labrador, Nova Scotia, Prince Edward Island, Saskatchewan or Ontario. We cannot ship treaments outside of these provinces at this time.

Does Felix replace my doctor?

No. Felix provides a faster, hassle-free way for you to get a prescription to certain medications but our service does not replace your primary care provider. For matters that extend beyond obtaining a prescription lifestyle medication safely and easily, we encourage you to consult your primary health practitioner in person — whether for checkups, personal health concerns, or to inform them about the medications you are currently using.

Can I be accurately assessed remotely?

Absolutely. Our online assessments have been designed to ask all the necessary questions required for diagnosis. We've worked with specialist to create an assessment process that can provide sufficient information for the healthcare practitioner to determine whether or not you are eligible for a prescription and craft an appropriate treatment plan.

It's an emergency. What do I do?

Call 911 or proceed to your nearest emergency room immediately. Felix is not intended for medical emergencies. Once the emergency has been addressed or resolved, contact your prescribing practitioner to inform them of your experience as this may impact your current treatment plan.

Online Visits

How does this visit work?

After creating an account, you will complete a medical assessment for evaluation by one of the Felix healthcare practitioners. 

During your assessment, you will have the opportunity to send your practitioner questions via secure messaging.  

In most cases, practitioners will complete your assessment with secure messaging alone but sometimes they may determine you require an audio or video visit and/or further diagnostic testing to help determine the best treatment plan for you. 

If your practitioner has determined a prescription treatment is appropriate, they will approve your visit and write you a prescription. Our pharmacy will then ship your prescription to your home.

You’ll be able to message your healthcare practitioner if you have questions or want to make changes to your treatment at any time.

Do I need to complete my online visit at a scheduled time?

No. We use an asynchronous telemedicine model so you can complete your online visit in your own time and we save your progress so you can come back later to finish it.

If you are completing a visit in the mental health or weight loss categories, your healthcare practitioner may require a phone or video call to discuss your medical profile further during the assessment process.

Does the online visit require a phone or video appointment?

Most assessments do not require a phone or video conversation. Once a prescriber has reviewed the info in your assessment they will respond to you via secure instant messages that you can access within your Felix account.  

If you are completing a visit in the mental health or weight loss categories, your healthcare practitioner may require a phone or video call to discuss your medical profile further during the assessment process.

How quickly will a healthcare practitioner review my online visit?

You can expect to receive a response from a healthcare practitioner within 24 hours of submission. If you’ve been waiting longer than this, please email and we’ll look into it.

Can I just get the treatment and skip the online visit?

No. A visit with a licensed healthcare practitioner is required for all treatments currently provided through Felix’s service.

Please email our Customer Support team at and they will be able to assist you with the transfer.

Privacy and Security

Is my information private and secure?

Yes, your security is paramount to Felix’s mission. Personal health information provided during your medical assessment is strictly and legally confidential between you and the Felix healthcare practitioner.

Beyond that, all your account information (including the medical assessment, credit card, and shipping information, etc.) is also stored safely and securely. Felix is compliant with all federal and provincial health privacy legislation. It is our duty to protect your data with comprehensive security infrastructure and stringent data policies to ensure it stays private and secure.

Read more on our Privacy Policy.

Is this legal?

Yes! In Canada, only a licensed healthcare practitioner can write a prescription, and only a registered pharmacist can fill that prescription. We are supported by leaders in the Canadian pharmacology and specialized medical fields. Felix adheres strictly to all the regulations set forth by all applicable Colleges of Pharmacists and Colleges of Physicians and Surgeons in which we operate.

Is this safe?

Absolutely. All prescriptions obtained via Felix are provided by licensed Canadian healthcare practitioners—the same as you would get at a hospital, doctor’s office, or clinic. These practitioners do not provide prescriptions unless they deem it medically safe and appropriate to write them based on your medical profile and assessment answers. Our assessments have been crafted by the experts on our medical team. Finally, all Felix Pharmacies are provincially accredited just like any retail pharmacy.

How is my privacy protected?

Your privacy is our top priority. All your data is 256 bit SSL/TLS encrypted, and we take significant steps to keep your data secure. You can read our Privacy Policy for more information. 


How long will it take to get my treatment?

Not long. After completing your assessment, a practitioner will generally respond within 24 hours, and often much sooner.

Treatment plans will be processed within 2-3 business days of your approval date if there is nothing blocking fulfillment.

All packages are shipped via Express Post, which usually takes 2-3 business days. You will receive an email with your tracking number once your treatment has been shipped.

Is your packaging discreet?

Absolutely. All Felix shipments arrive in a nondescript blister package so you can have your treatment shipped wherever makes sense for you as long as there is someone there to sign for it.

Do I have to be home to receive my package?

A signature upon delivery may be required.

How much does it cost to ship my treatment?

There is currently no cost to have your treatment shipped to you from our Felix Pharmacy network.

What courier do you use for shipping?

Our pharmacy partners use Canada Post and/or Purolator for shipping.

Pricing and Payment

How much is the online visit?

Felix charges a fee for the online visit, but only if and when you are approved by the healthcare practitioner. In most cases the fee is $40 but varies by treatment category. The visit fee includes a prescription valid for up to a year (depending on the condition) and on-going support from the healthcare practitioner or pharmacist.

How much will my treatment cost?

It depends. Treatment costs vary but will be in line with what you would pay at a pharmacy in person. You will see the estimated cost of your treatment before insurance, during the online visit but will only be charged once approved. Once approved, your treatment and payment will be processed within one to two days.

Keep in mind that you won’t necessarily need to pay the full price yourself. If you have insurance, Felix’s partner pharmacies will bill your insurer directly. You may also be eligible for financial support in your province.

What payment methods do you accept?

We accept all major credit cards for any aspect of your treatment not covered by insurance or other financial support

When am I charged?

You will be charged for the online visit as soon as it is approved by the healthcare practitioner. From there, and after your prescription is activated by the pharmacy, you will be charged the medication cost for each shipment based on your chosen refill schedule. If you have provided insurance or benefits coverage details, it will be applied according to your plan.


Am I covered by my insurance?

Treatment coverage varies greatly between different insurance plans.

The good news is that if you are covered, Felix can bill your insurer directly, and then process your treatment plan at no additional cost to you. We recommend that you upload your private and/or provincial benefit card during the online visit so that our pharmacy partner can apply any coverage you are eligible for before processing your treatment plan.

Insurance coverage for treatment plans through Felix doesn't include the cost of your visit.

Is the online visit covered by my insurance or provincial health plans?

A Felix online visit is considered asynchronous since it is conveniently completed through a secure chat bases system. Currently, asynchronous visits are not covered by insurance or provincial health plans so you will be charged a visit fee, depending on the category of treatment you are requesting.

Is the medication covered by my insurance or provincial health plans?

Medication coverage varies greatly between different plans, provinces, and has specific criteria that determine eligibility. For private insurance, we recommend contacting your benefits administrator with your details and the Drug Identification Number (DIN) and the drug name to determine your coverage.

For more details on provincial health plan coverage see below:

Alberta: Learn more about AHCIP here. Search for covered drugs here.

British Columbia: Learn more about MSP here. Search for covered drugs here.

Manitoba: Learn more about MHSIP here. Search for covered drugs here.

Newfoundland and Labrador: Learn more about MCP here. Search for covered drugs here.

Nova Scotia: Learn more about MSI here. Search for covered drugs here.

Ontario: Learn more about OHIP+ here. Search for covered drugs here.

Prince Edward Island: Learn more about Health PEI here. Search for covered drugs here.

Saskatchewan: Learn more about Saskatchewan Health Coverage here. Search for covered drugs here.

Is birth control covered by OHIP in Ontario?

OHIP+ covers some birth control for eligible residents of Ontario who are under 25 years old and do not have private insurance. You can check if your birth control medication is covered here. Make sure to upload your Ontario health card during your online visit so our pharmacy partners can apply your coverage directly.

Have more questions? We’ve got answers.
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