Estragyn Vaginal Cream
Estrongen Vaginal Cream

Get your Estragyn medication filled online

With Felix, you can get Estragyn prescribed by a licensed healthcare practitioner and delivered to your door for free.

At a glance
Estrone 0.1% w/w
45g Tube
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What is

Estragyn vaginal cream is a topical medication containing the active ingredient estrone.

It’s used to treat certain symptoms (i.e., itching, burning, etc.), in and around the vagina, which is associated with lack of estrogen brought on by menopause.

It’s important to note that Estragyn cream is only indicated for use in women that have an intact uterus, unless it’s prescribed alongside progestin. Estragyn is only intended for short-term use.

For more resources, including a full list of the risks and benefits of Estragyn, please review the product monograph.

How does

When a person enters menopause, estrogen production slows and then stops. Although this is a natural, universal experience, it can lead to a number of different, uncomfortable symptoms.

One of these symptoms is thinning of the vagina walls, which can lead to itching, burning sensations, or dryness.

Estrone, the active ingredient in Estragyn cream, works by contributing to the growth of epithelial cells of the vaginal wall. In turn, it improves the thickness and elasticity of the vaginal walls. This aids in lubrication, as well as reduces vaginal dryness and itchiness.

What is
used to treat?

Estragyn’s primary indicated use is as a treatment for certain symptoms associated with menopause, including:

  • Vaginal dryness
  • Itchiness
  • Burning sensations

It’s important to note that Estragyn is only indicated for use in women that have an intact uterus, and this medication should only be taken under regular supervision of your healthcare practitioner.

This includes a follow-up visit with your prescriber within 3-6 months of starting your Estragyn treatments.

Due to the fact that this medication is only recommended for short-term use, it’s important to also discuss the risks vs benefits of taking Estragyn cream with your practitioner, before starting Estragyn.

How do you take

Dosing Estragyn cream can range from 0.5g to 4g daily, depending on your practitioner’s recommendation. Estragyn is administered intravaginally.

If you’ve been wondering how to use Estragyn cream, it’s recommended for use cyclically on a schedule of 3 weeks on, 1 week off. It’s always recommended to use the lowest dosage possible to control symptoms, and discontinue use as soon as is appropriate.

This is part of the reason that regular check-ups with your practitioner are suggested, so that you can revisit how effective the medication is working for you, and whether you need to continue with Estragyn treatments.

How long does
last after you take it?

What are the common side effects of

The most common side effects associated with Estragyn cream are spotting and changes in vaginal secretion, and you should speak with your practitioner if these symptoms continue beyond a few days.

Additionally, there are some serious side effects that occur more rarely with Estragyn dosages, but are important to be able to recognize. These include:

  • Abdominal pain
  • Nausea
  • Vomiting
  • Breast lumps
  • Chest heaviness or crushing chest pain
  • Pain or swelling in the legs
  • Persistent sad moods
  • Sharp pain in the chest, coughing blood, or sudden shortness of breath
  • Sudden partial or complete loss of vision
  • Sudden severe or worsening of headache
  • Dizziness or fainting
  • Disturbance of vision or speech
  • Weakness or numbness in an arm or leg
  • Unexpected vaginal bleeding
  • Jaundice (yellowing of the eyes or skin)

If you start to experience any of these serious side effects, be sure to contact your healthcare practitioner immediately.

Who shouldn't take

There are a number of people that shouldn’t use Estragyn cream, such as:

  • People with a hypersensitivity to estrone or any of the other ingredients in Estragyn
  • People with liver dysfunction (serious liver disease), or that have had liver function tests that have not yet returned to normal
  • People that have or have had cancer of the uterus or endometrium (lining of the womb), or any other estrogen-dependent cancers
  • People that have endometrial hyperplasia (overgrowth of the lining of the uterus)
  • People that have known, suspected, or a past history of breast cancer
  • People with undiagnosed, abnormal genital bleeding
  • People that are pregnant, or that may be pregnant
  • People that have active or a history of arterial thromboembolic disease (i.e., stroke, heart attack, coronary heart disease)
  • People that have or have a history of blood clots forming in the blood vessels of their legs (deep vein thrombosis), lungs (pulmonary embolism), or other organs
  • People with thrombophlebitis (painful inflammation of the veins in the legs)
  • People with vision issues caused by blood vessel disease of the eye (ophthalmic vascular disease)
  • People that are breastfeeding
  • People that use latex condoms for any reason
  • People that experience migraine headaches

In addition to these people, there are others that should be extra cautious about using Estragyn cream, such as people who:

  • Have a history of allergies or intolerances to other medications
  • Have a personal history of breast disease (including lumps), breast biopsies, or a family history of breast cancer
  • Have experienced any unusual or undiagnosed vaginal bleeding
  • Have a history of uterine fibroids or endometriosis
  • Have a history of liver disease, liver tumours, jaundice
  • Have experienced itching related to estrogen use or during pregnancy
  • Have a history of migraines
  • Have a history of high blood pressure
  • Have a personal or family history of blood clots
  • Have a personal history of heart disease or strokes
  • Have a history of kidney disease, asthma, or epilepsy
  • Have a history of bone disease, including metabolic conditions, or cancers that affect the levels of calcium of phosphorus in the blood
  • Have diabetes
  • Have porphyria (a blood pigment disease)
  • Have a history of high cholesterol or high triglycerides
  • Have had a hysterectomy
  • Have lupus
  • Have hearing loss due to otosclerosis
  • Are pregnant or may be pregnant
  • Smoke
  • Use latex condoms for any reason (may not compatible with the mineral oil found in Estragyn cream)
  • Have hereditary angioedema
  • Have experienced episodes of rapid swelling of the hands, feet, face, lips, eyes, tongue, throat (airway blockage), or digestive tract
  • Are breastfeeding

If any of these conditions apply to you, your healthcare practitioner may want to review the risks vs benefits of Estragyn with you, or potentially suggest an alternative medication that may work better for you.

Some other medications can interact negatively with Estragyn cream, so be sure to tell your practitioner if you’re on any other medications before starting Estragyn. This is especially important if you’re taking medications for:

  • High blood pressure
  • Diabetes
  • Blood clots
  • Sleeping
  • Anxiety
  • Seizures
  • Pain relief
  • Tuberculosis

Or if you’re taking certain over-the-counter medications, vitamins, or herbal products (i.e., St. John’s wort). The practitioner will be able to tell you whether Estragyn cream will potentially interact with any of the other medications you’re currently taking.

What happens if
is taken regularly by men?


We’d love to tell you more

Health Canada regulations require us to confirm your patient status to access further information on Estragyn.
The drug identification number (DIN) is easy to find. It’ll be printed on your Estragyn packaging and the receipt from your pharmacist.

Sorry the DIN you entered is incorrect. Please verify the number and try again.

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Trusted by over 500,000 Canadians

Very easy and professional experience. Quick response from the doctor and easy ordering, billing and shipped and delivered on time. Hassle free.
Great service and products. Everything always arrived in a timely manner.
Simple, respectful, professional with good follow up and guidance, and fast service and delivery.
Best place to get birth control. No more annoying doctor visits
Within an hour . . . a doctor contacted me to make sure that particular medication was what I wanted. Doctor was friendly and knowledgeable. Within minutes . . . being confirmed my order was put through and I received my medication after 2 days.
Great service! I really appreciate being able to put my auto-refill on pause.
Easy and simple.
The best service!!! So happy I never have to try and get myself to the pharmacy anymore. This is the future!!!
The whole process of signing up with Felix, the online visit, and getting my prescription in the mail was very easy and very convenient.
Super convenient, and amazing customer service! The team always responds +++ fast and answers every question and concern. Very pleased with Felix!
Discreet, quick, very professional, and feels totally safe. This is such a convenient service and I'm a huge fan already.
Sign up was a breeze, and items shipped faster than expected. A positive, painless experience from start to finish!
Felix gets you into contact with doctors discreetly online to address personal matters that you'd rather not go to a doctor in person to see, you get the prescription best suited to your needs, and they'll deliver it to your local pharmacy or even your house!
Very quick and easy to do. Can ask the doctor any questions about the medication.
The process was a whole lot easier and faster than I imagined. And the doctor was absolutely helpful and answered relatively fast. I highly recommend Felix.
Super convenient and affordable! Much easier than having to book a doctors appointment and wait to get a prescription filled.

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Frequently asked questions


Felix 101

What is Felix?

Felix is Canada’s first truly integrated healthcare platform. We provide on-demand treatment for everyday health needs like weight loss, mental health, sexual health, and more. Founded in 2019, our digital-first approach to healthcare includes everything from diagnosis to prescription — all accessible from the comfort of home.

Who can use Felix?

Anyone who is 18 years or older older (16 or older for acne and birth control prescriptions), and is located in Alberta, British Columbia, Manitoba, Newfoundland and Labrador, Nova Scotia, Prince Edward Island, Saskatchewan or Ontario. We cannot ship medication outside of these provinces at this time.

Does Felix replace my doctor?

No. Felix provides a faster, hassle-free way for you to get a prescription to certain medications but our service does not replace your primary care provider. For matters that extend beyond obtaining a prescription lifestyle medication safely and easily, we encourage you to consult your primary health practitioner in person — whether for checkups, personal health concerns, or to inform them about the medications you are currently using.

Can I be accurately assessed remotely?

Absolutely. Our online assessments have been designed to ask all the necessary questions required for diagnosis. We've worked with specialist to create an assessment process that can provide sufficient information for the healthcare practitioner to determine whether or not you are eligible for a prescription and craft an appropriate treatment plan.

It's an emergency. What do I do?

Call 911 or proceed to your nearest emergency room immediately. Felix is not intended for medical emergencies. Once the emergency has been addressed or resolved, contact your prescribing practitioner to inform them of your experience as this may impact your current treatment plan.

Online Visits

How does this visit work?

After creating an account, you will complete a medical assessment for evaluation by one of the Felix healthcare practitioners. 

During your assessment, you will have the opportunity to send your practitioner questions via secure messaging.  

In most cases, practitioners will complete your assessment with secure messaging alone but sometimes they may determine you require an audio or video visit and/or further diagnostic testing to help determine the best treatment plan for you. 

If your practitioner has determined a prescription treatment is appropriate, they will approve your visit and write you a prescription. Our pharmacy will then ship your prescription to your home.

You’ll be able to message your healthcare practitioner if you have questions about your medication or want to make changes to your treatment at any time.

Do I need to complete my online visit at a scheduled time?

No. We use an asynchronous telemedicine model so you can complete your online visit in your own time and we save your progress so you can come back later to finish it.

If you are completing a visit in the mental health or weight loss categories, your healthcare practitioner may require a phone or video call to discuss your medical profile further during the assessment process.

Does the online visit require a phone or video appointment?

Most assessments do not require a phone or video conversation. Once a prescriber has reviewed the info in your assessment they will respond to you via secure instant messages that you can access within your Felix account.  

If you are completing a visit in the mental health or weight loss categories, your healthcare practitioner may require a phone or video call to discuss your medical profile further during the assessment process.

How quickly will a healthcare practitioner review my online visit?

You can expect to receive a response from a healthcare practitioner within 24 hours of submission. If you’ve been waiting longer than this, please email and we’ll look into it.

Can I just get the medication and skip the online visit?

No. A prescription written by a licensed healthcare practitioner is required for all medication currently provided through Felix’s service. If you already have a prescription with at least one refill remaining, you can transfer it to the Felix Pharmacy network.

Please email our Customer Support team at and they will be able to assist you with the transfer.


How long will it take to get my medication?

Not long. After completing your assessment, a practitioner will generally respond within 24 hours, and often much sooner.

The pharmacy will process and fill your prescription within 2-3 business days of your prescription approval date if there is nothing blocking them from doing so.

All packages are shipped via Express Post, which usually takes 2-3 business days. You will receive an email with your tracking number once your treatment has been shipped.

Is your packaging discreet?

Absolutely. All Felix shipments arrive in a nondescript blister package so you can have your medication shipped wherever makes sense for you as long as there is someone there to sign for it.

Do I have to be home to receive my package?

A signature upon delivery may be required.

How much does it cost for shipping my medication?

There is currently no cost to have your medication sent to you from our Felix Pharmacy network.

What courier do you use for shipping?

Our pharmacy partners use Canada Post and/or Purolator for shipping.

Privacy and Security

Is my information private and secure?

Yes, your security is paramount to Felix’s mission. Personal health information provided during your medical assessment is strictly and legally confidential between you and the Felix healthcare practitioner.

Beyond that, all your account information (including the medical assessment, credit card, and shipping information, etc.) is also stored safely and securely. Felix is compliant with all federal and provincial health privacy legislation. It is our duty to protect your data with comprehensive security infrastructure and stringent data policies to ensure it stays private and secure.

Read more on our Privacy Policy.

Is this legal?

Yes! In Canada, only a licensed healthcare practitioner can write a prescription, and only a registered pharmacist can fill that prescription. We are supported by leaders in the Canadian pharmacology and specialized medical fields. Felix adheres strictly to all the regulations set forth by all applicable Colleges of Pharmacists and Colleges of Physicians and Surgeons in which we operate.

Is this safe?

Absolutely. All prescriptions obtained via Felix are provided by licensed Canadian healthcare practitioners—the same as you would get at a hospital, doctor’s office, or clinic. These practitioners do not provide prescriptions unless they deem it medically safe and appropriate to write them based on your medical profile and assessment answers. Our assessments have been crafted by the experts on our medical team. Finally, all Felix Pharmacies are provincially accredited just like any retail pharmacy.

How is my privacy protected?

Your privacy is our top priority. All your data is 256 bit SSL/TLS encrypted, and we take significant steps to keep your data secure. You can read our Privacy Policy for more information. 

Pricing and Payment

How much is the online visit?

Felix charges a fee for the online visit, but only if and when you are approved by the healthcare practitioner. In most cases the fee is $40 but varies by treatment category. The visit fee includes a prescription valid for up to a year (depending on the condition) and on-going support from the healthcare practitioner or pharmacist.

How much will my medication cost?

It depends. Medication costs vary from treatment to treatment but will be in line with what you would pay at a pharmacy in person. You will see the estimated cost of your medication before insurance, during the online visit but will only be charged once approved. Once approved, your prescription will be sent to the pharmacy and we will process the payment and fill the prescription within one to two days.

Keep in mind that you won’t necessarily need to pay the full price yourself. If you have insurance, Felix’s partner pharmacies will bill your insurer directly. You may also be eligible for financial support in your province.

What payment methods do you accept?

We accept all major credit cards for any aspect of your treatment not covered by insurance or other financial support

When am I charged?

You will be charged for the online visit as soon as it is approved by the healthcare practitioner. From there, and after your prescription is activated by the pharmacy, you will be charged the medication cost for each shipment based on your chosen refill schedule. If you have provided insurance or benefits coverage details, it will be applied according to your plan.


Am I covered by my insurance?

Medication coverage varies greatly between different insurance plans.

The good news is that if you are covered, Felix can bill your insurer directly, and then ship your medications right to your door at no additional cost to you. We recommend that you upload your private and/or provincial benefit card during the online visit so that our pharmacy partner can apply any coverage you are eligible for before shipping your meds.

Insurance coverage for medications through Felix doesn't include the cost of your visit.

Is the online visit covered by my insurance or provincial health plans?

A Felix online visit is considered asynchronous since it is conveniently completed through a secure chat bases system. Currently, asynchronous visits are not covered by insurance or provincial health plans so you will be charged a visit fee, depending on the category of treatment you are requesting.

Is the medication covered by my insurance or provincial health plans?

Medication coverage varies greatly between different plans, provinces, and has specific criteria that determine eligibility. For private insurance, we recommend contacting your benefits administrator with your details and the Drug Identification Number (DIN) and the drug name to determine your coverage.

For more details on provincial health plan coverage see below:

Alberta: Learn more about AHCIP here. Search for covered drugs here.

British Columbia: Learn more about MSP here. Search for covered drugs here.

Manitoba: Learn more about MHSIP here. Search for covered drugs here.

Newfoundland and Labrador: Learn more about MCP here. Search for covered drugs here.

Nova Scotia: Learn more about MSI here. Search for covered drugs here.

Ontario: Learn more about OHIP+ here. Search for covered drugs here.

Prince Edward Island: Learn more about Health PEI here. Search for covered drugs here.

Saskatchewan: Learn more about Saskatchewan Health Coverage here. Search for covered drugs here.

Is birth control covered by OHIP in Ontario?

OHIP+ covers some birth control for eligible residents of Ontario who are under 25 years old and do not have private insurance. You can check if your birth control medication is covered here. Make sure to upload your Ontario health card during your online visit so our pharmacy partners can apply your coverage directly.

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